There are no currently medically approved creams for the removal of skin tags. Skin tags are typically removed by physical methods like cutting off or tying off with dental floss. It is not advisable to use unapproved products like Dermasil, wart removers, tea tree oil, nail polish, toothpaste, or hair-removal creams like Neet or Nair. Trial uses of unapproved creams may cause irritation and possible secondary complications.
While the majority of skin tags are simply destroyed, sometimes tissue is sent for microscopic exam by a health care specialist known as a pathologist, who will determine the exact diagnosis and determine whether an abnormality such as skin cancer is present. Irregular skin growths that are larger, bleed, or have an unusual presentation may require pathology examination to make sure there are no irregular cells or skin cancers.
Don’t impulsively deem any protruding bump as a skin tag; after all, there is an overwhelming number of things it could be—moles and seborrheic keratoses can closely resemble skin tags. Even worse, it could be something that requires medical treatment such as genital warts (possible indication of a sexually transmitted disease). Some growths could also be an extension of glands on the skin, and they can get infected if you’re poking at them at home. As a rule of thumb, if the tag is pigmented, see a dermatologist to get it evaluated. And here are 11 other skin mysteries you should know about.
Treat with apple cider vinegar. Get a cotton ball and soak it in apple cider vinegar until it is totally saturated. Place the cotton ball on your skin tag and hold for a few minutes. You can move the ball in a circular motion on the skin to increase absorption if you like. Repeat this process three times per day until your skin tag falls off. This method is usually quite effective. Depending on your skin the vinegar may not be as effective so you can try using apple cider by itself. 
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Michelle Nguyen, a dermatologist and the director of Mohs micrographic surgery at Tufts Medical Center in Boston, tells Allure that what we call skin tags are really just benign skin lesions composed of normal skin tissue. New York City dermatologist Joshua Zeichner adds that skin tags, comprised of extra skin and fat, can happen to anyone. There is, however, a genetic component to them, and people whose parents had them are more likely to get them themselves.
Other skin conditions such as warts and moles can resemble skin tags. Since some moles may be cancerous, it’s best to have your skin tags examined by a doctor. Your dermatologist or family doctor will be able to diagnose skin tags. They’ll likely do this through a visual exam. If they have any doubt about the diagnosis, they may also perform a biopsy.