Tying skin tags off is a popular method to remove skin tags in a medical office. Until recently there weren’t many options available to do this easily and safely at home. Now you can find devices that do this for you that minimize the risk of infection. A popular device that does this for you is the Tagband Device. With this device that comes in a skin tag removal kit, you can easily get rid of your skin tags at home. Check out a step by step video on how to use it here.

Repetitive friction and wearing tight clothes may contribute to skin tags in people who are overweight. According to a medical paper written by dermatologists in Spain, an obese patient, whose job required repeating lifting of her arms, developed a pattern of skin tags along her bra straps from the constant friction. Avoiding tight clothing if you are overweight is suggested.
If you decide you want to get rid of your skin tags you can either have a medical provider do it or, in the case of small tags, do it yourself with a minimum of pain or bleeding. “If skin tags are small, you can remove them with sharp clean scissors, like cuticle scissors,” said Sorensen. “Or you can tie floss or thin thread at the base of the skin tag and leave it in place until the skin tag falls off.”

As far as other DIY methods for skin tag removal at home, such as applying apple cider vinegar, coconut oil, tea tree oil, etc., Geraghty notes that there's no compelling evidence to show that those therapies are effective. "You can't make tissue disappear by putting a little vinegar on it. It just doesn’t work... You really need that to physically be removed."
Essential oils contain anti-inflammatory and antimicrobial properties that may help remove skin tags naturally. One solution that's becoming popular is the use of tea tree oil, which is a potent product derived from the Melaleuca alternifolia tree from Australia.19 This plant has been studied extensively, with research pointing out that it can help fight bacteria,20 fungi21 and viruses.22 Furthermore, other experts note that tea tree oil contains anti-inflammatory properties.23,24,25
Insulin resistance, which may lead to type 2 diabetes and prediabetes, may also play a role in the development of skin tags. People with insulin resistance don’t absorb glucose effectively from the bloodstream. According to a 2010 study, the presence of multiple skin tags was associated with insulin resistance, a high body mass index, and high triglycerides.