Make a dermatologist appointment. The majority of skin tags are harmless, but it is best to talk with a dermatologist if you notice that the tag is darker than your skin color, large in size, or unusual in shape. If you remove the tag without consulting a professional you could lose valuable time in the event that it is a sign of a larger problem.
Some common skin tag look-alikes include benign lesions such as seborrheic keratoses, common moles, warts, neurofibromas, and a fatty mole called nevus lipomatosus. While extremely rare, there are a few reports of skin cancers found in skin tags. Skin cancers like basal cell carcinoma, squamous cell carcinoma, and malignant melanoma may rarely mimic skin tags, as described above.
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Congenital nevi are moles that are present at birth. Congenital nevi occur in about one in 100 people. These moles are slightly more likely to develop into melanoma (cancer) than are moles that appear after birth. A mole or freckle should be checked if it has a diameter of more than a pencil eraser or any characteristics of the ABCDEs of melanoma (see below).
Michelle Nguyen, a dermatologist and the director of Mohs micrographic surgery at Tufts Medical Center in Boston, tells Allure that what we call skin tags are really just benign skin lesions composed of normal skin tissue. New York City dermatologist Joshua Zeichner adds that skin tags, comprised of extra skin and fat, can happen to anyone. There is, however, a genetic component to them, and people whose parents had them are more likely to get them themselves.