While they can turn up anywhere, skin tags tend to appear where there is frequent friction, such as the neck, breasts, groin, and underarms. Ultimately, there is no evidence that skin tags will lead to any serious skin condition: They’re mostly an aesthetic annoyance. Regardless, most dermatologists encourage you to have them checked out—and removed, if you want. The only link to danger is from one study from the Indian Journal of Dermatology, which suggested that skin tags may be a sign of underlying heart issues. You could get your heart checked out, but the one research connection shouldn’t concern anyone too much.
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As far as other DIY methods for skin tag removal at home, such as applying apple cider vinegar, coconut oil, tea tree oil, etc., Geraghty notes that there's no compelling evidence to show that those therapies are effective. "You can't make tissue disappear by putting a little vinegar on it. It just doesn’t work... You really need that to physically be removed."
What are some clear signs you should ask your dermatologist whether or not a mole needs a biopsy? If your mole is asymmetrical, has an irregular border, contains different colors, has a diameter larger than a pencil eraser, or is evolving in some way, you should mention it to your doctor. These are known as the ABCDEs of melanoma, according to the American Academy of Dermatology, because they signify when a mole may be cancerous.
Other skin conditions such as warts and moles can resemble skin tags. Since some moles may be cancerous, it’s best to have your skin tags examined by a doctor. Your dermatologist or family doctor will be able to diagnose skin tags. They’ll likely do this through a visual exam. If they have any doubt about the diagnosis, they may also perform a biopsy.