Dr Yip notes that while it’s uncommon to experience an infected skin tag, it’s likely they may become red, inflamed and itchy if they're constantly rubbing against clothing and jewellery. “If there is infection, it is usually red, swollen and painful and may have pus discharge and a malodour [an unpleasant odour].” If this occurs, apply an antiseptic cream to mild irritations or see a dermatologist if the pain is more severe.
Rub on aloe vera. You can either snip off a piece of an aloe vera plant or squeeze it to get the gel or you can purchase a bottle of aloe vera gel at a store. Get a cotton swab and dip it in the gel. Wipe it on your tag as often as you like. This method relies on the natural curative properties of aloe vera and its effectiveness is hit or miss.[12]

The punch biopsy has been done, and now the area has the mole in the middle but not yet removed. It will be taken out with forceps (a tweezer-like instrument) and put in a specimen bottle to be sent to the lab for analysis. It is important that every mole be sent for analysis in order to make sure that no atypical cells remain or that it isn't a precancerous type of mole. Photo courtesy Joel Schlessinger, MD, Board Certified Dermatologist, lovelyskin.com.Click to view larger image.

Generally, they do not cause any pain or discomfort. However, if they are subjected to friction or damage caused by clothing or jewelry, a small blood clot may occur, resulting in pain. While it may be tempting at that point to simply cut it off, this is not an acceptable way to remove a skin tag. The best practices for how to remove skin tags at home do not involve cutting; this is dangerous and may lead to a severe infection and permanent scarring.
Apple cider vinegar can destroy the skin tag tissue so that it goes away completely. Take two tablespoons of apple cider vinegar and soak a cotton ball with this. Apply it to the skin tag after completely cleansing the skin and drying it. Make sure to squeeze the cotton ball while you massage the skin tag so that the skin tag is saturated with the vinegar.
There are a few ways that moles may be removed to create a more attractive appearance. When the growth is superficial and raised, we may perform a shave excision. Comfort is a priority, and we achieve this with the use of local anesthetic before mole removal procedures. The shave technique involves a transverse incision that “shaves” the growth from the skin's surface. In many cases, this results in healing into a barely perceptible scar.
If the skin tag is very small, the first thing Geraghty does is spray the bump with cold liquid nitrogen, a non-toxic substance. It's sprayed out of a can and is approximately -320 degrees Fahrenheit. “We direct this very cold spray of gas onto the spot for a few seconds, then we take a break and then we do a few seconds more and usually that’s enough to make the skin tag fall off within a few days,” said Geraghty.
Insulin resistance, which may lead to type 2 diabetes and prediabetes, may also play a role in the development of skin tags. People with insulin resistance don’t absorb glucose effectively from the bloodstream. According to a 2010 study, the presence of multiple skin tags was associated with insulin resistance, a high body mass index, and high triglycerides.