While the majority of skin tags are simply destroyed, sometimes tissue is sent for microscopic exam by a health care specialist known as a pathologist, who will determine the exact diagnosis and determine whether an abnormality such as skin cancer is present. Irregular skin growths that are larger, bleed, or have an unusual presentation may require pathology examination to make sure there are no irregular cells or skin cancers.
And speaking of cancer, it’s generally not something you need to worry about with regular old skin tags. Dr. Farber says that, “If anything changes quickly, is unusually painful, or concerns you, it’s worth getting it examined to confirm it’s a benign skin tag …. Skin tags tend to grow very slowly. Any growth that changes quickly is a reason to get examined by a dermatologist.”